Description

Azathioprine Sodium is the sodium salt form of the immunosuppressive prodrug azathioprine, offering enhanced solubility for pharmaceutical formulations. This compound is critical for its role in modulating immune responses, making it a key active pharmaceutical ingredient (API) in targeted therapies. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for autoimmune disorders and in transplant medicine to prevent organ rejection.

Application

• Immunosuppressive Pharmaceutical Formulations: As a key API in injectable and oral dosage forms for autoimmune diseases like rheumatoid arthritis, lupus, and inflammatory bowel disease.
• Organ Transplant Rejection Prophylaxis: Used in the manufacture of medications to prevent the immune system from attacking transplanted organs such as kidneys and hearts.
• Clinical Research & Development: Serves as a reference standard and raw material in preclinical and clinical studies for novel immunosuppressive therapies.
• Veterinary Medicine: Applied in the formulation of treatments for autoimmune conditions in companion animals.
• Bulk Pharmaceutical Manufacturing: Supplied to contract manufacturing organizations (CMOs) for the large-scale production of finished drug products.
• Biochemical Research: Utilized in laboratory studies investigating purine metabolism and the mechanisms of immunosuppression.

Basic Information

Product Name	Azathioprine Sodium
CAS No.	55774-33-9
Molecular Formula	C9H7N7NaO2S
Molecular Weight	300.26 g/mol
Synonyms	Azathioprine Sodium Salt; Sodium Azathioprine; Azathioprine Na; 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine Sodium Salt; Imuran (Sodium Salt); AZA Sodium; BW 57-322S; Azamun
EINECS	Contact for details

Quality Control

Our Azathioprine Sodium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with comprehensive analysis covering identity, potency, and impurity profiles. A Certificate of Analysis (COA) is provided with each shipment, detailing results against relevant pharmacopeial specifications (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.