Description

Neodigoxin is a potent cardiac glycoside derivative, structurally related to digoxin, with significant pharmacological activity. This high-purity compound is critical for research and development in cardiovascular pharmacology and serves as a key reference standard. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Cardiovascular Research: Serves as a crucial tool in biochemical and pharmacological studies to investigate mechanisms of cardiac glycosides, sodium-potassium ATPase inhibition, and inotropic effects.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of novel cardiac therapeutic agents and related derivatives.
• Analytical Testing: Essential for calibrating equipment and conducting comparative analyses in HPLC, LC-MS, and other chromatographic assays.
• Metabolite Studies: Used in research to study the metabolism, pharmacokinetics, and pharmacodynamics of digoxin and related compounds.

Basic Information

Product Name	Neodigoxin
CAS No.	55576-67-5
Molecular Formula	C₄₁H₆₄O₁₄
Molecular Weight	780.94 g/mol
Synonyms	Neodigoxin; 3β,12β,14-Trihydroxy-5β-card-20(22)-enolide 3-(2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranoside); 12β-Hydroxydigoxin; Gitoxin 12β-hydroxy derivative; 12-Hydroxydigoxin; Card-20(22)-enolide, 3-[(2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
EINECS	Contact for details

Quality Control

Our Neodigoxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.