Description

(R)-3,3'-Dimethyl-1,1'-Binaphthalene-2,2'-Diol CAS NO 55515-98-5 is a high-purity, enantiomerically pure binaphthol derivative, a crucial chiral auxiliary and ligand in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in a wide range of catalytic and stoichiometric organic transformations, directly impacting the efficiency and cost of producing single-enantiomer compounds. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance chiral building blocks.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal complexes (e.g., with Ti, B, Al, Cu) used in asymmetric C-C bond formations, oxidations, and reductions.
• Pharmaceutical Intermediate Synthesis: Critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system and cardiovascular drugs.
• Chiral Resolution Agent: Used to prepare chiral stationary phases for HPLC or as a resolving agent for racemic mixtures.
• Organocatalysis: Functions as a chiral Brønsted acid catalyst or as a core structure for designing novel organocatalysts.
• Advanced Material Precursor: Employed in the synthesis of chiral polymers, liquid crystals, and molecular devices with specific optical properties.
• Agrochemical Synthesis: Key intermediate for producing chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profile.

Basic Information

Product Name	(R)-3,3'-Dimethyl-1,1'-Binaphthalene-2,2'-Diol
CAS No.	55515-98-5
Molecular Formula	C22H18O2
Molecular Weight	314.38 g/mol
Synonyms	(R)-3,3'-Dimethyl-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Dimethyl-BINOL; (R)-3,3'-Dimethyl-1,1'-bi-2-naphthol; (R)-3,3'-Dimethyl-[1,1'-binaphthalene]-2,2'-diol; (R)-3,3'-Dimethyl-2,2'-dihydroxy-1,1'-binaphthalene; (R)-3,3'-DMBINOL; (R)-3,3'-Dimethylbinaphthol; (R)-3,3'-Dimethyl-1,1'-binaphthyl-2,2'-diol
EINECS	Contact for details

Quality Control

Every batch of (R)-3,3'-Dimethyl-1,1'-Binaphthalene-2,2'-Diol is manufactured and tested under strict quality management systems to ensure consistent high purity and enantiomeric excess (e.e.). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as chiral purity (HPLC), chemical purity, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% e.e.
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.