Description

L-Aspartic Acid-13C4, 15N, 99 Atom % 13C is a high-purity, isotopically labeled derivative of the essential amino acid L-aspartic acid, uniformly enriched with carbon-13 and nitrogen-15. This compound is critical for advanced research requiring precise metabolic pathway tracing and quantification in proteomics, metabolomics, and pharmaceutical development. It is an indispensable tool for scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require the highest standards of isotopic purity and chemical stability for their tracer studies and internal standard applications.

Application

• Stable Isotope Labeled Internal Standards for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Metabolic Flux Analysis (MFA) and tracer studies to investigate cellular metabolism, amino acid biosynthesis, and the urea cycle.
• Proteomics Research, serving as a labeled building block for the synthesis of isotopically labeled peptides and proteins for mass spectrometry-based protein quantification (e.g., SILAC, AQUA).
• Pharmaceutical R&D for drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Nutritional Science Research to study protein turnover, amino acid absorption, and whole-body metabolism in clinical and preclinical models.
• NMR Spectroscopy as a enriched substrate to simplify complex spectra and enhance signal detection in structural and dynamic studies of biomolecules.

Basic Information

Product Name	L-Aspartic Acid-13C4, 15N, 99 Atom % 13C
CAS No.	55443-54-4
Molecular Formula	¹³C₄H₇¹⁵NO₄
Molecular Weight	136.06 (based on ¹³C=13.0034, ¹⁵N=15.0001)
Synonyms	(2S)-2-Aminobutanedioic-13C4,15N acid; L-Aspartic-13C4,15N acid; (S)-Aminosuccinic-13C4,15N acid; Aspartic acid-13C4,15N (L-form); U-13C4,15N-L-Aspartic acid; 13C4,15N-L-Asp; 13C4,15N-L-Aspartic Acid; Uniformly Labeled 13C4,15N-L-Aspartic Acid
EINECS	Contact for details

Quality Control

Every batch of our L-Aspartic Acid-13C4, 15N is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (Atom % 13C and 15N), chemical purity by HPLC, chiral purity, and residual solvent analysis. Our quality systems are designed to meet the rigorous demands of analytical and research applications, ensuring reliable and reproducible performance in your most sensitive experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Isotopic Enrichment (Atom % 15N)	≥ 98%
Chemical Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.