Description

(S)-2-(4-Fluorophenyl)-3-Methylbutyric Acid is a high-purity chiral building block and key pharmaceutical intermediate. Its value lies in its defined stereochemistry, which is crucial for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental profile.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in chiral separation techniques like HPLC.

Basic Information

Product Name	(S)-2-(4-Fluorophenyl)-3-Methylbutyric Acid
CAS No.	55332-37-1
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	(S)-2-(p-Fluorophenyl)-3-methylbutanoic Acid; (S)-2-(4-Fluorophenyl)-3-methylbutanoic Acid; (S)-α-Isopropyl-4-fluorobenzeneacetic Acid; (S)-3-Methyl-2-(4-fluorophenyl)butyric Acid; (2S)-2-(4-Fluorophenyl)-3-methylbutanoic Acid; (S)-Flurbiprofen Impurity; (S)-FMPBA
EINECS	Contact for details

Quality Control

Every batch of (S)-2-(4-Fluorophenyl)-3-Methylbutyric Acid is produced under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, NMR, and MS, to ensure identity, purity, and enantiomeric excess (e.e.) meet the highest standards. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.