Description

(S)-2-Hydroxypentanedioic Acid Diethyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters because its defined stereochemistry is crucial for producing enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurologic and metabolic drugs.
• Asymmetric Synthesis: Used as a starting material or auxiliary in stereoselective reactions to construct complex molecular architectures.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring specific chirality.
• Academic & R&D Laboratories: Utilized in methodological research for new catalytic processes and synthetic route development.

Basic Information

Product Name	(S)-2-Hydroxypentanedioic Acid Diethyl Ester
CAS No.	55094-99-0
Molecular Formula	C9H16O5
Molecular Weight	204.22 g/mol
Synonyms	(S)-2-Hydroxyglutaric Acid Diethyl Ester; Diethyl (S)-2-Hydroxyglutarate; (S)-Diethyl 2-Hydroxypentanedioate; (S)-2-Hydroxy-1,5-pentanedioic Acid Diethyl Ester; L-2-Hydroxyglutaric Acid Diethyl Ester; (S)-HGA Diethyl Ester; Ethyl (S)-2-Hydroxyglutarate; (2S)-2-Hydroxypentanedioic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxypentanedioic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and specific rotation values are provided to guarantee reproducible quality and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.