Description

Epinephrine Glucuronide is a major, water-soluble metabolite of the neurotransmitter and hormone epinephrine (adrenaline). This compound is crucial for researchers and developers in the life sciences, as it serves as a key biomarker for studying adrenergic system activity, drug metabolism, and physiological stress responses. It is primarily utilized in pharmaceutical research, clinical diagnostics, and the development of analytical reference standards.

Application

• Biomarker Research: Used as a reference standard in metabolomic and pharmacokinetic studies to quantify epinephrine metabolism and clearance rates.
• Clinical Diagnostics: Serves as a critical calibrant in LC-MS/MS and HPLC assays for accurately measuring catecholamine metabolites in patient samples (e.g., urine, plasma).
• Pharmaceutical Development: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies for drugs affecting the sympathetic nervous system.
• Enzymology Studies: Used as a substrate to study the activity of UDP-glucuronosyltransferase (UGT) enzymes involved in phase II drug metabolism.
• Reference Standard: Essential for quality control and method validation in analytical laboratories to ensure accuracy and reproducibility.
• Physiological Stress Research: A key analyte in research investigating the biochemical pathways of stress, exercise, and cardiovascular function.

Basic Information

Product Name	Epinephrine Glucuronide
CAS No.	54964-61-3
Molecular Formula	C15H19NO9
Molecular Weight	357.31 g/mol
Synonyms	Adrenaline Glucuronide; (-)-Epinephrine Glucuronide; L-Epinephrine Glucuronide; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol β-D-Glucopyranosiduronic Acid; Epinephrine D-Glucuronide; Adrenaline β-D-Glucuronide; 3,4-Dihydroxy-α-[(methylamino)methyl]benzyl alcohol D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our Epinephrine Glucuronide is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Total impurities ≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.