Description

cis-Tranylcypromine Hydrochloride is a high-purity, stereochemically defined hydrochloride salt of the monoamine oxidase inhibitor (MAOI) tranylcypromine. This compound is critical for pharmaceutical research and development, particularly in the study of neurological pathways and the development of novel therapeutic agents. It serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the neuropharmacology sector.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Neurological Research: A vital tool for in vitro and in vivo studies targeting monoamine oxidase enzymes, relevant to depression and anxiety research.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of final drug formulations.
• Biochemical Assay Development: Employed in high-throughput screening and enzyme inhibition assays.
• Metabolite and Impurity Profiling: Essential for identifying and quantifying related substances in compliance with ICH guidelines.

Basic Information

Product Name	cis-Tranylcypromine Hydrochloride
CAS No.	54779-58-7
Molecular Formula	C9H12ClN
Molecular Weight	169.65 g/mol
Synonyms	(1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride; (1S,2R)-Tranylcypromine hydrochloride; (-)-trans-2-Phenylcyclopropylamine hydrochloride; Parnate hydrochloride (stereoisomer); TCP hydrochloride; MAOI hydrochloride; cis-2-Phenylcyclopropylamine hydrochloride
EINECS	Contact for details

Quality Control

Our cis-Tranylcypromine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research and pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% cis-isomer
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.