Description

Clovoxamine CAS NO 54739-19-4 is a selective serotonin reuptake inhibitor (SSRI) compound of significant interest in pharmaceutical research and development. This high-purity chemical intermediate is crucial for the synthesis of advanced active pharmaceutical ingredients (APIs) targeting central nervous system disorders. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in the development of next-generation neuropsychiatric therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antidepressant and anxiolytic Active Pharmaceutical Ingredients (APIs).
• Research & Development: Critical reference standard and precursor in medicinal chemistry programs for central nervous system (CNS) drug discovery.
• Preclinical Studies: Used in pharmacological and toxicological studies to investigate the efficacy and safety profiles of SSRI-based compounds.
• Analytical Standard: Serves as a high-purity standard for method development and quality control (QC) in analytical laboratories (HPLC, GC-MS).
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial pharmaceutical manufacturing.

Basic Information

Product Name	Clovoxamine
CAS No.	54739-19-4
Molecular Formula	C16H16ClF2N3O
Molecular Weight	339.77 g/mol
Synonyms	Clovoxamine; DU 23811; 5-[(2,4-Dichlorophenyl)methoxy]-2-(dimethylamino)-2-phenylpentanenitrile; 5-[(2,4-Dichlorobenzyl)oxy]-α,α-dimethyl-γ-oxo-benzenebutanenitrile; DU-23811; Benzenebutanenitrile, 5-[(2,4-dichlorophenyl)methoxy]-α,α-dimethyl-γ-oxo-
EINECS	Contact for details

Quality Control

Our Clovoxamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, ensuring the material meets the stringent requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.