Description

(R)-5-Phenyl-1,3-Dioxolane-2,4-Dione CAS NO 54256-33-6 is a high-purity chiral building block and intermediate of significant synthetic utility. Its value lies in its role as a versatile precursor for the synthesis of optically active compounds, particularly in the development of pharmaceuticals and advanced materials. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with defined stereochemistry via reactions like aldol condensations and nucleophilic additions.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for stereoselective transformations.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, flavors, fragrances, and advanced polymeric materials requiring precise molecular architecture.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(R)-5-Phenyl-1,3-Dioxolane-2,4-Dione
CAS No.	54256-33-6
Molecular Formula	C9H6O4
Molecular Weight	178.14 g/mol
Synonyms	(R)-5-Phenyl-1,3-dioxolane-2,4-dione; (R)-Phenylglyceric Acid Lactone; (R)-α-Phenylglyceric Acid γ-Lactone; (R)-3-Phenyl-2-oxetanone-4-carboxylic Acid Lactone; (R)-2,4-Dioxo-5-phenyl-1,3-dioxolane; (R)-Phenyl-1,3-dioxolane-2,4-dione; (R)-Benzaldehyde Cyanohydrin Carbonate Cyclic Ester
EINECS	Contact for details

Quality Control

Our (R)-5-Phenyl-1,3-Dioxolane-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.