Description

2-Fluoro-3-(4-Hydroxyphenyl)Propanoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for creating next-generation drug candidates, particularly in therapeutic areas requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances compound stability and bioactivity.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into complex molecules to mimic peptide structures and improve pharmacological properties.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and structure-activity relationships (SAR) in academic and industrial settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Fluoro-3-(4-Hydroxyphenyl)Propanoic Acid
CAS No.	53786-98-4
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	3-(4-Hydroxyphenyl)-2-fluoropropanoic Acid; 2-Fluoro-3-(4-hydroxyphenyl)propionic Acid; 4-Hydroxy-2-fluorohydrocinnamic Acid; 2-Fluoro-3-(p-hydroxyphenyl)propanoic Acid; (2R/S)-2-Fluoro-3-(4-hydroxyphenyl)propanoic Acid; DL-2-Fluoro-3-(4-hydroxyphenyl)propionic Acid; β-Fluoro-4-hydroxyhydrocinnamic Acid; Fluorohydroxyphenylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(4-Hydroxyphenyl)Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.