Description

Nivalin P CAS NO 53321-09-8 is a high-purity pharmaceutical active ingredient, also known by its common name Galantamine Hydrobromide. This compound is a selective, competitive, and reversible acetylcholinesterase inhibitor, making it a critical component in the synthesis of advanced neurological therapeutics. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing treatments for neurodegenerative conditions.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of prescription medications for Alzheimer's disease and other forms of dementia.
• Neurological Research: Used as a reference standard and key reagent in preclinical and clinical studies investigating cholinergic system function.
• Finished Dosage Form Production: Incorporated into tablets, capsules, and oral solutions for final pharmaceutical products.
• Analytical Standard: Serves as a high-purity calibrant in quality control laboratories for HPLC, LC-MS, and other chromatographic assays.
• Chemical Synthesis Intermediate: Used in the synthesis of more complex galantamine derivatives and analogs for drug discovery programs.

Basic Information

Product Name	Nivalin P
CAS No.	53321-09-8
Molecular Formula	C17H21NO3 • HBr
Molecular Weight	368.27 g/mol
Synonyms	Galantamine Hydrobromide; Galanthamine Hydrobromide; Nivalin®; Lycoremine; Jilkon; Reminyl; Razadyne; (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide
EINECS	Contact for details

Quality Control

Our Nivalin P is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.