Description

(1R,2R)-N,N,N',N'-Tetramethyl-1,2-cyclohexanediamine is a high-purity, chiral diamine ligand and organocatalyst. This compound is valued for its role in asymmetric synthesis, where it facilitates the creation of enantiomerically pure molecules critical for advanced pharmaceuticals and fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, such as hydrogenation and alkylation.
• As an organocatalyst for enantioselective synthesis in pharmaceutical intermediate manufacturing.
• In the development of novel catalytic systems for academic and industrial research.
• As a key building block for synthesizing complex, stereodefined molecules in fine chemical production.
• In methodological studies for the creation of new carbon-carbon and carbon-heteroatom bonds.
• For the resolution of racemic mixtures via diastereomeric salt formation or catalytic kinetic resolution.

Basic Information

Product Name	(1R,2R)-N,N,N',N'-Tetramethyl-1,2-cyclohexanediamine
CAS No.	53152-69-5
Molecular Formula	C10H22N2
Molecular Weight	170.30 g/mol
Synonyms	(1R,2R)-(-)-1,2-Bis(dimethylamino)cyclohexane; (1R,2R)-TMCDA; (1R,2R)-Tetramethylcyclohexanediamine; (1R,2R)-N,N,N',N'-Tetramethyl-1,2-diaminocyclohexane; (1R,2R)-1,2-Diamino-1,2-bis(dimethylamino)cyclohexane; (-)-TMCDA; (R,R)-TMCDA; Chiral TMCDA
EINECS	Contact for details

Quality Control

Our (1R,2R)-N,N,N',N'-Tetramethyl-1,2-cyclohexanediamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical assay, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.