Description

Ent-Corey Pg-Lactone Diol CAS NO 53110-06-8 is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional group array, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), fine chemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of prostaglandin analogs and other bioactive molecules.
• Asymmetric Synthesis: Utilized as a starting material or building block for constructing stereochemically defined compounds in medicinal chemistry.
• Fine Chemical Production: Serves as a critical intermediate in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Industrial Research: Used in methodological development and exploratory synthesis for new chemical entities.
• Process Chemistry: Employed in route scouting and optimization for scalable manufacturing of target molecules.

Basic Information

Product Name	Ent-Corey Pg-Lactone Diol
CAS No.	53110-06-8
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	(15S)-15-Hydroxy-9-oxoprosta-5,13-dien-1-oic acid, γ-lactone, 11,15-dihydroxy derivative; ent-9-Deoxy-9,10-didehydro-15-deoxy-16-hydroxy-16-methyl PGF2α γ-lactone diol; Corey Lactone Diol enantiomer; PGL Diol; Prostaglandin Lactone Diol Intermediate; (-)-Corey Lactone Diol; ent-PGF2α Lactone Diol
EINECS	Contact for details

Quality Control

Our Ent-Corey Pg-Lactone Diol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chiral purity assessment, to meet the exacting standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.