Description

Deoxycholic Acid-24-13C is a stable isotope-labeled analog of deoxycholic acid, a primary bile acid, where the carbon atom at the 24-position is enriched with the 13C isotope. This compound is an essential tool for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway tracing via mass spectrometry. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions engaged in lipid metabolism studies, drug development, and biomarker discovery.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analyses for accurate measurement of endogenous deoxycholic acid and related bile acids in biological matrices.
• Metabolic Pathway Tracing: Enables the study of bile acid synthesis, enterohepatic circulation, and microbial metabolism in the gut using isotope-labeled tracer techniques.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates the investigation of drug-bile acid interactions and the pharmacokinetic profiling of compounds affecting bile acid pathways.
• Clinical Diagnostics Research: Supports the development and validation of assays for bile acid disorders, such as cholestasis and metabolic diseases.
• Biomarker Discovery: Aids in the identification and validation of bile acid signatures associated with liver disease, intestinal disorders, and metabolic syndromes.
• Stable Isotope Labeling in Chemical Synthesis: Serves as a labeled building block for the synthesis of more complex isotopically labeled compounds for research.

Basic Information

Product Name	Deoxycholic Acid-24-13C
CAS No.	52886-37-0
Molecular Formula	C24H4013CO4
Molecular Weight	Contact for details
Synonyms	3α,12α-Dihydroxy-5β-cholan-24-oic-24-13C acid; (3α,5β,12α)-3,12-Dihydroxycholan-24-oic-24-13C acid; 13C-Labeled Deoxycholic Acid; [24-13C]-Deoxycholic Acid; DCA-24-13C; 7-Deoxycholic Acid-24-13C; Desoxycholic Acid-24-13C
EINECS	Contact for details

Quality Control

Our Deoxycholic Acid-24-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (by titration)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.