Description

Ambenonium Dichloride is a quaternary ammonium compound that functions as a reversible acetylcholinesterase inhibitor. This pharmacological activity makes it a critical intermediate and reference standard in the research and development of therapeutic agents targeting neuromuscular function. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel acetylcholinesterase inhibitors for potential therapeutic applications.
• Biochemical Research: Used as a reference standard and tool compound in enzymatic studies to investigate cholinesterase activity and inhibition kinetics.
• Neuromuscular Research: Employed in preclinical studies to model and understand conditions related to acetylcholine signaling.
• Fine Chemical Synthesis: Serves as a specialized reagent for the preparation of other quaternary ammonium compounds with biological activity.
• Quality Control & Analytical Standards: Essential for developing and validating analytical methods (e.g., HPLC, LC-MS) for pharmaceutical quality assurance.

Basic Information

Product Name	Ambenonium Dichloride
CAS No.	52022-31-8
Molecular Formula	C28H42Cl2N4O2
Molecular Weight	537.57 g/mol
Synonyms	Ambenonium Chloride; WIN 8077; N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl) chloride; Oxamide, N,N'-bis[2-(diethylamino)ethyl]-N,N'-bis(2-chlorobenzyl)-, dichloride; 1,1'-[Oxalylbis(imino-2,1-ethanediyl)]bis[N-(2-chlorobenzyl)-N,N-diethylammonium] Dichloride
EINECS	257-599-5

Quality Control

Our Ambenonium Dichloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from methods including HPLC, NMR, and mass spectrometry. Our quality commitment supports applications in research and development where reliable and traceable materials are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.