Description

(1R, 2R, 5S)-Neomenthyl Amine is a high-purity, chiral amine derivative of menthol, characterized by its specific stereochemistry. This compound matters as a versatile and valuable chiral building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing advanced active ingredients and catalysts.

Application

• Chiral Auxiliary/Resolving Agent: Used for the separation of enantiomers (optical isomers) of racemic acids via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemical configurations.
• Catalyst Ligand Precursor: Employed in the development of chiral ligands for asymmetric catalysis, such as hydrogenation and alkylation reactions.
• Agrochemical Synthesis: Utilized in the production of enantiomerically pure herbicides, pesticides, and plant growth regulators.
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing high-value chiral aroma chemicals and flavor compounds.
• Academic & Industrial Research: A critical reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(1R, 2R, 5S)-Neomenthyl Amine
CAS No.	51743-63-6
Molecular Formula	C10H21N
Molecular Weight	155.28 g/mol
Synonyms	(1R,2R,5S)-2-Isopropyl-5-methylcyclohexanamine; (-)-Neomenthylamine; (1R,2R,5S)-Neomenthylamine; (1R,2R,5S)-2-(1-Methylethyl)-5-methylcyclohexanamine; L-Neomenthylamine; (1R,2R,5S)-1-Methyl-2-(1-methylethyl)-5-aminocyclohexane; Neomenthan-2-amine
EINECS	Contact for details

Quality Control

Our (1R, 2R, 5S)-Neomenthyl Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC or GC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.