Description

(R)-Epibromohydrine CAS NO 51594-57-1 is a chiral building block of significant importance in asymmetric synthesis. This optically active epoxide is a versatile intermediate for constructing complex molecules with defined stereochemistry. It is primarily needed by the pharmaceutical, agrochemical, and fine chemical industries for the development of active pharmaceutical ingredients (APIs), chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in β-blocker and antiviral research.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex natural products, flavors, and fragrances.
• Polymer Modification: Can be used to introduce chiral epoxide functionalities into polymer chains for specialty materials.
• Academic & R&D: A valuable reagent in research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-Epibromohydrine
CAS No.	51594-57-1
Molecular Formula	C3H5BrO
Molecular Weight	136.98 g/mol
Synonyms	(R)-(-)-Epibromohydrin; (R)-1-Bromo-2,3-epoxypropane; (R)-3-Bromo-1,2-epoxypropane; (2R)-(-)-1-Bromo-2,3-epoxypropane; (R)-(-)-1-Bromo-2,3-epoxypropane; (R)-3-Bromopropylene oxide; (R)-Glycidyl bromide; (R)-Oxirane, (bromomethyl)-
EINECS	Contact for details

Quality Control

Our (R)-Epibromohydrine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC or GC, to ensure compliance with high-purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.485
Specific Rotation ([α]20D)	-30° to -35° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.