Description

Limbitrol is a pharmaceutical compound primarily recognized for its use in the formulation of antidepressant and anxiolytic medications. This active pharmaceutical ingredient (API) is critical for ensuring the efficacy and consistency of finished drug products targeting central nervous system disorders. It is essential for manufacturers in the global pharmaceutical and life sciences industries who require a reliable, high-purity supply for research, development, and commercial production.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of prescription antidepressant medications.
• Key component in the development of anxiolytic (anti-anxiety) drug products.
• Utilized in pharmaceutical research and development (R&D) for studying neuropharmacology and drug mechanisms.
• Reference standard in analytical laboratories for quality control and method validation of drug formulations.
• Starting material or intermediate in the synthesis of more complex pharmaceutical compounds.
• Used in clinical trial material manufacturing for investigational new drugs.

Basic Information

Product Name	Limbitrol
CAS No.	51248-68-1
Molecular Formula	C₂₃H₂₇ClN₂O
Molecular Weight	382.93 g/mol
Synonyms	Amitriptyline Hydrochloride and Chlordiazepoxide; Chlordiazepoxide and Amitriptyline Hydrochloride; Limbitrol (Trade Name); 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine compound with 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 4-oxide hydrochloride; 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene hydrochloride compound with 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide
EINECS	Contact for details

Quality Control

Our Limbitrol is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to confirm compliance with relevant pharmacopeial standards (such as USP or EP) and customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.