Description

(S)-(-)-1,1-Diphenyl-1,2-Propanediol Cyclic Sulfite CAS NO 51226-54-1 is a high-purity chiral sulfite derivative, serving as a critical chiral auxiliary and intermediate in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, which is essential for producing enantiomerically pure pharmaceuticals and advanced materials. This compound is particularly needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce chirality in the synthesis of enantiomerically pure compounds, crucial for pharmaceutical active ingredients.
• Pharmaceutical Intermediate: A key building block in the research and production of specific drug candidates, particularly in central nervous system (CNS) and cardiovascular therapies.
• Catalyst and Ligand Precursor: Employed in the development of chiral catalysts and ligands for transition metal-catalyzed reactions.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Material Science Research: Investigated for the synthesis of chiral polymers and liquid crystals with unique optical properties.
• Academic and R&D Laboratories: A valuable tool for methodological development in organic chemistry and stereochemistry studies.

Basic Information

Product Name	(S)-(-)-1,1-Diphenyl-1,2-Propanediol Cyclic Sulfite
CAS No.	51226-54-1
Molecular Formula	C15H14O3S
Molecular Weight	274.33 g/mol
Synonyms	(S)-1,1-Diphenyl-1,2-ethanediol cyclic sulfite; (S)-DPED Sulfite; (S)-(-)-DPED Cyclic Sulfite; (4S)-4,5-Dihydro-4,5-diphenyl-1,3,2-dioxathiole 2-oxide; (S)-1,1-Diphenyl-1,2-ethanediol 1,2-cyclic sulfite; (S)-Styrene glycol diphenyl cyclic sulfite; (S)-Cyclic sulfite of 1,1-diphenyl-1,2-ethanediol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical applications. Each batch is characterized to confirm identity, purity, and enantiomeric excess (ee). Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.