Description

Benzoic Acid, 2-Amino-, Labeled With Tritium (9Ci) is a high-specific-activity radiolabeled compound, specifically the tritiated form of 2-Aminobenzoic acid (Anthranilic acid). This product is essential for advanced research requiring precise metabolic and pharmacokinetic tracking. It is primarily used by pharmaceutical, agrochemical, and academic research institutions for radioligand binding assays, autoradiography, and ADME (Absorption, Distribution, Metabolism, and Excretion) studies. The high specific activity of 9Ci/mmol enables sensitive detection in trace analysis applications.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to study the metabolic pathways, bioavailability, and clearance of new chemical entities in preclinical research.
• Biochemical Receptor Binding Assays: Serves as a radioligand for investigating receptor-ligand interactions and determining binding affinities.
• Autoradiography: Enables the visualization and spatial localization of compounds in tissue sections for toxicology and pathology research.
• Environmental Fate Studies: Tracks the degradation, transformation, and mobility of chemical analogs in environmental science and agrochemical research.
• Metabolic Pathway Elucidation: Aids in identifying and quantifying metabolites in complex biological matrices.
• Quality Control for Radiolabeled Compounds: Used as a reference standard in the production and validation of other labeled materials.

Basic Information

Item	Detail
Product Name	Benzoic Acid, 2-Amino-, Labeled With Tritium (9Ci)
CAS No.	50816-84-7
Molecular Formula	C7H5NO2 (³H labeled)
Molecular Weight	~139.12 g/mol (unlabeled)
Synonyms	2-Aminobenzoic Acid-³H; Anthranilic Acid-³H; Tritiated Anthranilic Acid; [³H]-2-Aminobenzoic Acid; o-Aminobenzoic Acid-³H; Vitamin L1 (labeled); 2-Amino-³H-benzoic Acid; Benzoc Acid, 2-Amino-, Tritiated
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is produced and tested under strict quality control protocols to ensure radiochemical purity, specific activity, and chemical stability. Analysis is performed via HPLC with radiometric detection. A comprehensive Certificate of Analysis (COA) detailing specific activity (Ci/mmol), radiochemical purity (%), chemical purity, and solvent composition is provided with each shipment to ensure compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store the solution at the recommended temperature (typically -20°C or as specified on the COA) in a designated, appropriately shielded area for radioactive materials. Ensure compliance with all local and international regulations for the handling and storage of radioactive substances.

Specification

Item	Specification
Appearance	Clear solution (color may vary)
Specific Activity	~9 Ci/mmol
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	Contact for details
Concentration	1 mCi/mL (or as specified)
Solvent	Ethanol/Water or custom
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.