Description

Dl-Erythro/Threo Sphinganine (D16:0) CAS NO 50731-08-3 is a high-purity, synthetic diastereomeric mixture of the sphingoid base sphinganine, a fundamental building block for complex sphingolipids. This compound is critical for researchers and manufacturers requiring a defined, high-quality precursor for lipidomics, biochemical pathway studies, and the synthesis of more complex bioactive sphingolipids. It is essential for applications in pharmaceutical research, life science reagent development, and advanced material science where precise lipid structures are required.

Application

• Biochemical Research & Lipidomics: Used as a standard and precursor in the study of sphingolipid metabolism, cell signaling pathways, and membrane biology.
• Pharmaceutical Intermediate: Serves as a key starting material for the synthesis of ceramides, glycosphingolipids, and other sphingolipid-based drug candidates.
• Life Science Reagents: Incorporated into assay kits, diagnostic tools, and research reagents for studying apoptosis, cell proliferation, and stress responses.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for quality control and method validation in lipid analysis.
• Cosmetic Science: Investigated for use in advanced skincare formulations targeting skin barrier function and ceramide replenishment.
• Nutritional Research: Studied for its role and effects as a bioactive lipid component in nutritional supplements and functional foods.

Basic Information

Product Name	Dl-Erythro/Threo Sphinganine (D16:0)
CAS No.	50731-08-3
Molecular Formula	C16H35NO2
Molecular Weight	273.46 g/mol
Synonyms	D-erythro-Dihydro-D-sphingosine; (2S,3R)-2-Amino-1,3-octadecanediol; D-erythro-Sphinganine; Dihydro-D-sphingosine; (2S,3R)-2-Aminooctadecane-1,3-diol; C18 Dihydroceramide backbone; 2S,3R-Octadecasphinganine; D-erythro-C18-Sphinganine
EINECS	Contact for details

Quality Control

Our Dl-Erythro/Threo Sphinganine (D16:0) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, diastereomeric ratio, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Total of Erythro/Threo isomers)
Diastereomeric Ratio (Erythro:Threo)	Approx. 1:1 (Contact for specific batch data)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.