Description

Phenylthiohydantoin Lysine) CAS NO 5789-16-2 is a specialized derivative of lysine, primarily used as a key intermediate in peptide and protein chemistry. This compound is essential for researchers and manufacturers requiring high-purity building blocks for Edman degradation sequencing and the synthesis of modified peptides. It is critically important for pharmaceutical R&D, biotechnology, and advanced diagnostic reagent production where precise molecular structure and purity are paramount.

Application

• Peptide Sequencing: A critical reagent in the Edman degradation process for determining the amino acid sequence of peptides and proteins.
• Pharmaceutical Intermediates: Serves as a high-purity building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in proteomics and metabolomics studies for protein characterization and biomarker discovery.
• Diagnostic Reagents: Employed in the development of advanced diagnostic kits and assays for clinical and research laboratories.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and method validation in analytical chemistry.
• Academic & Industrial R&D: Fundamental material for investigating post-translational modifications and protein-ligand interactions.

Basic Information

Product Name	Phenylthiohydantoin Lysine) CAS NO 5789-16-2
CAS No.	5789-16-2
Molecular Formula	C15H19N3O3S
Molecular Weight	321.40 g/mol
Synonyms	PTH-Lysine; 2-[(Phenylcarbamothioyl)amino]-6-aminohexanoic acid; Lysine Phenylthiohydantoin; PTH-Lys; L-Lysine, N2-[(phenylamino)thioxomethyl]-; Edman Degradation Derivative of Lysine; 5-(4,5-Dihydro-5-thioxo-1H-imidazol-2-yl)-L-norvaline; N-Phenylthiocarbamoyl-L-lysine
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Lysine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.