Description

(2R)-2-Phenylbutane is a chiral organic compound belonging to the class of alkylbenzenes. This specific enantiomer is of significant value in advanced chemical synthesis, particularly for its role as a chiral building block and resolving agent. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and specialty materials. The compound's defined stereochemistry is critical for applications requiring high enantiomeric purity.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) where stereochemistry is crucial for biological activity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in homogeneous catalysis.
• Chiral Solvent or Additive: Employed in stereoselective reactions to influence enantiomeric excess (ee).
• Reference Standard for Analytical Chemistry: Used in chromatography (GC, HPLC) for method development and calibration in chiral separations.
• Building Block for Advanced Materials: Incorporated into liquid crystals or polymers where the chiral center imparts specific optical or physical properties.
• Academic and Industrial Research: A key reagent for studying reaction mechanisms and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	(2R)-2-Phenylbutane
CAS No.	5787-29-1
Molecular Formula	C10H14
Molecular Weight	134.22 g/mol
Synonyms	(R)-(-)-2-Phenylbutane; (R)-2-Phenylbutane; (-)-2-Phenylbutane; (R)-sec-Butylbenzene; (2R)-2-Fenylbutaan; (R)-1-Methyl-1-phenylpropane; (R)-α-Ethyltoluene; Benzene, (1R)-1-methylpropyl-
EINECS	Contact for details

Quality Control

Our (2R)-2-Phenylbutane is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC)	≥ 99.0% ee
Refractive Index (n20D)	1.488 - 1.492
Specific Rotation ([α]D20)	-30.0° to -34.0° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.