Description

Butriptyline Hydrochloride is a tricyclic antidepressant (TCA) compound, primarily utilized in pharmaceutical research and development. Its significance lies in its role as a reference standard and active pharmaceutical ingredient (API) for investigating neuropharmacological pathways and therapeutic applications. This product is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in the development and quality control of neuroactive compounds. The material is supplied as a high-purity solid, meeting the stringent requirements for scientific and industrial use.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Active Pharmaceutical Ingredient (API): Serves as the key therapeutic component in the formulation of antidepressant medications for clinical research purposes.
• Biochemical Research: Employed in neuroscience and pharmacology studies to investigate the mechanisms of action of tricyclic antidepressants on neurotransmitter reuptake inhibition.
• Metabolite Studies: Used in the synthesis and analysis of metabolic derivatives for pharmacokinetic and toxicological profiling.
• Analytical Chemistry: Acts as a high-purity standard for calibration in techniques such as High-Performance Liquid Chromatography (HPLC), Mass Spectrometry (MS), and Nuclear Magnetic Resonance (NMR).

Basic Information

Product Name	Butriptyline Hydrochloride
CAS No.	5585-73-9
Molecular Formula	C21H27N•HCl
Molecular Weight	329.91 g/mol
Synonyms	10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine Hydrochloride; Butriptyline HCl; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene Hydrochloride; Evadyne; Centroton; AY-62014
EINECS	226-982-8

Quality Control

Our Butriptyline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, aligning with pharmaceutical-grade expectations. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents. We support compliance with relevant pharmacopeial standards (e.g., USP, EP) and regulatory frameworks (e.g., ICH Q7, GMP) for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and purity. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.