Description

3-Bromooxolane-2,5-Dione is a versatile brominated succinimide derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its ability to act as a selective brominating agent and a reactive intermediate for introducing functional complexity. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring brominated heterocycles or succinimide motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where bromine incorporation is critical for bioactivity.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal or mechanical properties.
• Organic Synthesis Reagent: Employed as a selective brominating agent for alkenes, alkynes, and aromatic compounds under mild conditions.
• Material Science Research: Intermediate in the production of advanced materials, including liquid crystals and organic semiconductors.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form complex carbon-carbon bonds.

Basic Information

Product Name	3-Bromooxolane-2,5-Dione
CAS No.	5470-44-0
Molecular Formula	C4H3BrO3
Molecular Weight	178.97 g/mol
Synonyms	3-Bromosuccinimide; N-Bromosuccinimide (NBS); 3-Bromo-2,5-dihydrofuran-2,5-dione; 1-Bromo-2,5-pyrrolidinedione; Succinimide, N-bromo-; Bromosuccinimide; NSC 92938; Bromosuccimide
EINECS	226-796-4

Quality Control

Every batch of 3-Bromooxolane-2,5-Dione is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards, and a detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. Our quality assurance protocols are designed to meet the stringent requirements of cGMP and ISO standards for reliable and reproducible performance in critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent decomposition. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	173 - 178 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.