Description

Oxithiopurinol is a specialized purine analog with significant utility in pharmaceutical research and development. Its primary value lies in its role as a key intermediate and reference standard for the synthesis and analytical validation of therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on metabolic and anti-inflammatory drug discovery. The product is supplied as a high-purity material to ensure reliable and reproducible results in critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, LC-MS, and other analytical techniques.
• Biochemical Research: Employed in enzymatic studies and as a tool compound for investigating purine metabolism pathways.
• Drug Discovery & Development: Acts as a precursor or model compound in the R&D of novel xanthine oxidase inhibitors and related therapeutics.
• Metabolite Studies: Utilized in the identification and quantification of metabolic products in pharmacokinetic research.

Basic Information

Product Name	Oxithiopurinol
CAS No.	5334-33-8
Molecular Formula	C5H4N4OS
Molecular Weight	168.18 g/mol
Synonyms	1H-Pyrazolo[3,4-d]pyrimidine-4-thiol, 6-hydroxy-; 6-Hydroxy-1H-pyrazolo[3,4-d]pyrimidine-4-thiol; 4-Thioallopurinol; 4-Mercapto-6-hydroxypyrazolo[3,4-d]pyrimidine; Oxypurinol thioether; Allopurinol metabolite thiol derivative
EINECS	226-246-7

Quality Control

Our Oxithiopurinol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.