Description

Lactose [D-Glucose 1-14C] CAS NO 5160-35-0 is a radiolabeled derivative of lactose, specifically labeled with carbon-14 at the C-1 position of the D-glucose moiety. This compound is an essential tracer for metabolic and biochemical research, enabling precise tracking of lactose and galactose metabolism in biological systems. It is primarily utilized by research scientists and pharmaceutical developers in the fields of metabolomics, drug development, and nutritional studies.

Application

• Metabolic Pathway Tracing: Used as a radiotracer to study the absorption, distribution, metabolism, and excretion (ADME) of lactose and its components in vivo and in vitro.
• Pharmaceutical Research: Critical for investigating the mechanism of action and metabolic fate of new drugs targeting lactose-related pathways or disorders like lactose intolerance.
• Biochemical Assay Development: Serves as a standard or substrate in enzymatic assays for lactase and other galactosidases.
• Nutritional Science Studies: Employed to trace the metabolic utilization of dietary lactose in animal models and cell cultures.
• Microbial Metabolism Research: Used to study lactose fermentation and metabolism in bacteria and other microorganisms.
• Autoradiography and Imaging: Facilitates the localization of lactose metabolites in tissues and cells for diagnostic and research purposes.

Basic Information

Item	Detail
Product Name	Lactose [D-Glucose 1-14C]
CAS No.	5160-35-0
Molecular Formula	C12H22O11 (with 14C label at specified position)
Molecular Weight	342.30 g/mol (unlabeled)
Synonyms	4-O-β-D-Galactopyranosyl-D-[1-14C]glucose; D-[1-14C]Glucose-β-D-galactoside; [1-14C]Lactose; β-Lactose-[1-14C]; Radiolabeled Lactose; Carbon-14 Labeled Lactose; 14C-Lactose; Milk Sugar-[1-14C]
EINECS	Contact for details

Quality Control

Every batch of Lactose [D-Glucose 1-14C] is manufactured and tested under strict quality systems to ensure high radiochemical purity and specific activity. Our quality commitment includes verification of identity, radiochemical purity by HPLC, and specific activity measurement. Certificates of Analysis (COA) detailing all analytical results, including purity and radioactivity data, are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider conditions recommended for radiolabeled compounds to minimize radiolytic decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Chemical Purity (HPLC)	≥ 98%
Solvent (for solutions)	Specified aqueous or ethanol solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.