Description

(4-Hydroxyphenyl)Diphenylphosphine is a versatile organophosphorus compound featuring a phenolic hydroxyl group, making it a valuable bifunctional ligand and building block. Its primary value lies in its ability to act as a ligand in transition metal catalysis and as a key intermediate in the synthesis of advanced materials and pharmaceuticals. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, agrochemical synthesis, and specialty polymer production, where precise molecular control is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phosphine-based ligands or functional groups.
• Catalyst Ligand: Serves as a ligand in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex organic molecules.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides that incorporate phosphine functionalities.
• Polymer Additive & Stabilizer: Acts as a stabilizer or co-monomer in the production of high-performance polymers and resins to enhance properties.
• Material Science Research: Employed in the development of novel organic electronic materials, metal-organic frameworks (MOFs), and functional surfaces.
• Chemical Synthesis Reagent: Utilized as a nucleophile or reducing agent in specialized organic synthesis protocols.

Basic Information

Product Name	(4-Hydroxyphenyl)Diphenylphosphine
CAS No.	5068-21-3
Molecular Formula	C18H15OP
Molecular Weight	278.29 g/mol
Synonyms	4-(Diphenylphosphino)phenol; p-Hydroxydiphenylphosphine; (4-Hydroxyphenyl)diphenylphosphane; Phenol, 4-(diphenylphosphino)-; 4-Diphenylphosphanylphenol; 4-Hydroxytriphenylphosphine; p-Diphenylphosphinophenol; 4-(Diphenylphosphanyl)phenol
EINECS	225-769-5

Quality Control

Our (4-Hydroxyphenyl)Diphenylphosphine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This material is easily oxidized and light-sensitive. Keep away from strong oxidizing agents and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.