Description

Glycopyrrolate CAS NO 596-51-0 is a quaternary ammonium anticholinergic agent, valued for its potent and selective inhibition of muscarinic acetylcholine receptors. Its primary commercial significance lies in its critical role as an active pharmaceutical ingredient (API) in the formulation of various therapeutic and pre-operative medications. This compound is essential for manufacturers in the pharmaceutical, veterinary medicine, and fine chemical synthesis sectors.

Application

• Pharmaceutical API: Core ingredient in medications for reducing secretions (e.g., in chronic obstructive pulmonary disease) and managing peptic ulcers.
• Pre-Anesthetic Medication: Used to inhibit salivation and bronchial secretions before surgery and to block cardiac vagal reflexes.
• Hyperhidrosis Treatment: Formulated into topical solutions or systemic treatments for severe, uncontrollable sweating.
• Gastrointestinal Disorders: Employed in drugs for managing irritable bowel syndrome and other functional GI disorders.
• Veterinary Medicine: Used as an antispasmodic and antisecretory agent in animal healthcare.
• Chemical Intermediate: Serves as a key synthetic building block in advanced organic chemistry and research.
• Ophthalmic Solutions: Component in eye drops for pupillary dilation during ocular surgery or examinations.

Basic Information

Product Name	Glycopyrrolate
CAS No.	596-51-0
Molecular Formula	C19H28BrNO3
Molecular Weight	398.34 g/mol
Synonyms	Glycopyrronium Bromide; 3-[(Cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethylpyrrolidinium Bromide; Robinul; AHR-504; Glycopyrrolate Bromide; Nuvig; Seebri
EINECS	209-889-7

Quality Control

Our Glycopyrrolate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards, typically conforming to USP, Ph. Eur., and CP monographs. Comprehensive testing includes identification, assay, impurity profile, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.