Description

(1R,3S)-(-)-Camphoric Anhydride CAS NO 595-29-9 is a high-purity, chiral bicyclic anhydride derived from natural camphor, serving as a critical chiral building block and resolving agent in asymmetric synthesis. Its enantiomeric purity and rigid molecular framework make it invaluable for introducing specific stereochemistry into complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, such as antiviral or neurological drugs.
• Asymmetric Catalyst and Ligand Precursor: Serves as a starting material for synthesizing chiral catalysts and ligands used in enantioselective reactions.
• Optical Resolution Agent: Employed to separate racemic mixtures of amines, alcohols, or acids into their enantiomerically pure components.
• Polymer and Specialty Materials Chemistry: Acts as a monomer or cross-linking agent for creating polymers with specific thermal or optical properties.
• Agrochemical Research: Utilized in the development of chiral pesticides and herbicides where biological activity is stereospecific.
• Academic and R&D Laboratories: A key reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(1R,3S)-(-)-Camphoric Anhydride
CAS No.	595-29-9
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	(-)-Camphoric Anhydride; (1R,3S)-Camphoric Anhydride; L-(-)-Camphoric Anhydride; (1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride; (1R)-(-)-Camphoric Acid Anhydride; NSC 403779; Bicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 1,7,7-trimethyl-, (1R,2S,4R)-, anhydride
EINECS	209-865-7

Quality Control

Our (1R,3S)-(-)-Camphoric Anhydride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	218 - 222 °C
Specific Rotation [α]20/D	-48° to -52° (c=1 in chloroform)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.