Description

Ethyl 2-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester, a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring a strategically positioned trifluoromethyl group, imparts unique electronic and steric properties essential for modifying the activity and stability of target molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring the lipophilicity and metabolic stability conferred by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and hydrolysis reactions to introduce the 2-(trifluoromethyl)benzoyl moiety into more complex molecular architectures.
• Chemical Research & Development: Essential for medicinal chemistry programs and material science research exploring structure-activity relationships (SAR).

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)Benzoate
CAS No.	577-62-8
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Ethyl o-(Trifluoromethyl)benzoate; 2-(Trifluoromethyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl α,α,α-Trifluoro-o-toluate; o-Trifluoromethylbenzoic Acid Ethyl Ester; Ethyl 2-(Trifluoromethyl)benzoate
EINECS	209-410-5

Quality Control

Our Ethyl 2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (20°C)	1.25 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.