Description

3α,14β-Dihydroxy-5β,14β-Carda-20(22)-Enolide is a high-purity cardenolide derivative, a class of compounds known for their potent biological activity. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for cardiovascular studies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors requiring a reliable, high-quality building block for active pharmaceutical ingredient (API) development and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of cardiac glycosides and related therapeutic agents.
• Biochemical Research: Used as a reference standard and probe in studies of Na+/K+-ATPase inhibition and cardiac cell signaling pathways.
• Analytical Standard: Employed in High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) for method development, calibration, and quality control of related compounds.
• Fine Chemical Synthesis: A valuable starting material for the semi-synthesis of novel steroid-based compounds with potential biological activity.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological investigations of cardenolides.

Basic Information

Product Name	3α,14β-Dihydroxy-5β,14β-Carda-20(22)-Enolide
CAS No.	545-52-8
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	3α,14β-Dihydroxy-5β-card-20(22)-enolide; 3α,14β-Dihydroxy-5β,14β-card-20(22)-enolide; 3α,14β-Dihydroxy-5β-carda-20(22)-enolide; Cardenolide derivative; 5β,14β-Carda-20(22)-enolide-3α,14β-diol; 3α,14β-Dihydroxy-5β,14β-card-20(22)-enolide (ambiguous); 3α,14β-Dihydroxy-5β,14β-carda-20(22)-enolide (ambiguous)
EINECS	Contact for details

Quality Control

Our 3α,14β-Dihydroxy-5β,14β-Carda-20(22)-Enolide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.