Description

Cinchonidine Sulfate is a high-purity alkaloid salt derived from cinchona bark, valued for its role as a chiral selector and resolving agent. Its primary commercial significance lies in its ability to facilitate the separation of enantiomers, which is critical for producing optically pure compounds in advanced synthesis. This product is essential for research laboratories and industrial-scale manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality chiral auxiliaries for asymmetric synthesis and analytical method development.

Application

• As a chiral resolving agent for the separation of racemic mixtures of carboxylic acids and other acidic compounds.
• Utilized as a chiral selector in the preparation of stationary phases for High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE).
• Employed in asymmetric synthesis as a catalyst or ligand precursor for stereoselective transformations.
• Used in pharmaceutical research and development for the preparation of enantiomerically pure drug intermediates.
• Applied in academic and industrial research for studying chirality and developing new analytical methodologies.
• Serves as a reference standard in quality control laboratories for analytical method validation.

Basic Information

Product Name	Cinchonidine Sulfate
CAS No.	524-61-8
Molecular Formula	C19H22N2O • H2SO4
Molecular Weight	366.45 g/mol
Synonyms	(8S,9R)-Cinchonan-9-ol Sulfate; Cinchonan-9-ol, (8alpha,9R)-, Sulfate (2:1); Cinchonidine, Sulfate; Dihydrocinchonine Sulfate; (9R)-Cinchonidine Sulfate; Cinchonidine Hydrogen Sulfate; Cinchotine Sulfate
EINECS	208-357-8

Quality Control

Our Cinchonidine Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for research and industrial applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.