Description

Trimipramine Maleate Salt is the maleate salt form of the tricyclic antidepressant compound trimipramine. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and batch-to-batch consistency of finished pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of antidepressant medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antidepressant drug products.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Clinical Research: Used in preclinical and clinical studies investigating psychotropic therapies and neuropharmacology.
• Formulation Development: Employed in R&D for developing new dosage forms such as tablets, capsules, or controlled-release systems.
• Generic Drug Manufacturing: A key starting material for producing generic versions of trimipramine-based medications.

Basic Information

Product Name	Trimipramine Maleate Salt
CAS No.	521-78-8
Molecular Formula	C23H29N3.C4H4O4
Molecular Weight	511.60 g/mol
Synonyms	Trimipramine maleate; 5-(3-Dimethylamino-2-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine maleate; Surmontil (brand name salt); Trimeprimine maleate; Trimipramini maleas; Trimipraminum; NSC-108161; 521-78-8
EINECS	Contact for details

Quality Control

Our Trimipramine Maleate Salt is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for identity, purity, and impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.