Description

Neostigmine is a synthetic parasympathomimetic agent and reversible acetylcholinesterase inhibitor. This compound is critical for its role in neuromuscular function, making it a key active pharmaceutical ingredient (API) in therapeutic formulations. It is primarily required by pharmaceutical manufacturers and research institutions for the production of medications and in biochemical studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable solutions and tablets for the treatment of myasthenia gravis.
• Postoperative Care: Used to reverse the effects of non-depolarizing neuromuscular blocking agents after surgery.
• Diagnostic Agent: Employed in diagnostic tests for myasthenia gravis (Tensilon test).
• Research Chemical: Utilized in pharmacological and neurological research to study cholinergic systems and neuromuscular junction physiology.
• Veterinary Medicine: Application in veterinary practice for similar neuromuscular indications in animals.

Basic Information

Product Name	Neostigmine
CAS No.	59-99-4
Molecular Formula	C12H19BrN2O2
Molecular Weight	303.20 g/mol
Synonyms	Neostigmine Bromide; (3-[(Dimethylamino)carbonyl]oxy)-N,N,N-trimethylbenzenaminium Bromide; Prostigmin Bromide; Neostigmina; Neoeserine; Synstigmin Bromide; Ro 2-3198; EINECS 200-452-3
EINECS	200-452-3

Quality Control

Our Neostigmine is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance includes compliance with relevant pharmacopoeial monographs (e.g., USP, EP). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and regulatory support for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.