Description

Hyoscine Hydrochloride is a high-purity pharmaceutical active ingredient, also known as Scopolamine Hydrochloride, with the CAS registry number 55-16-3. This anticholinergic agent is a critical component in the formulation of medications for motion sickness, postoperative nausea, and gastrointestinal spasms. It is essential for pharmaceutical manufacturers, research institutions, and developers of transdermal delivery systems requiring a reliable and well-characterized active pharmaceutical ingredient (API).

Application

• Pharmaceutical API: Primary active ingredient in injectable and oral formulations for motion sickness prevention and treatment.
• Transdermal Therapeutic Systems: Key component in patches designed for controlled, long-term delivery to manage nausea and vomiting.
• Pre-anesthetic Medication: Used to reduce salivary and bronchial secretions before surgery.
• Gastrointestinal Antispasmodics: Formulated in medications to relieve cramps and spasms of the stomach, intestines, and bladder.
• Ophthalmic Solutions: Used in diagnostic procedures to cause cycloplegia (paralysis of the ciliary muscle) and mydriasis (pupil dilation).
• Biochemical Research: Used as a muscarinic acetylcholine receptor antagonist in neurological and pharmacological studies.
• Veterinary Medicine: Employed as a sedative and antiemetic in animal healthcare.

Basic Information

Product Name	Hyoscine Hydrochloride
CAS No.	55-16-3
Molecular Formula	C17H21NO4·HCl
Molecular Weight	339.81 g/mol
Synonyms	Scopolamine Hydrochloride; (-)-Scopolamine Hydrochloride; 6β,7β-Epoxy-3α-tropanyl S-(-)-tropate Hydrochloride; Hyoscine HCl; Belladonnine Hydrochloride; Transderm-Scop (API); Buscopan (API component); L-Hyoscine Hydrochloride
EINECS	200-230-5

Quality Control

Our Hyoscine Hydrochloride is manufactured under strict quality management systems. It is typically tested to meet or exceed relevant pharmacopoeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the stringent requirements for pharmaceutical use. We are committed to supply chain transparency and regulatory compliance (e.g., ICH guidelines, cGMP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	-24° to -28° (c = 5 in H2O)
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.