Description

3,4-Diaminopyridine is a high-purity organic compound primarily used as a critical pharmaceutical intermediate and a versatile building block in chemical synthesis. Its value lies in its unique diamine-substituted pyridine structure, which enables its role in developing active pharmaceutical ingredients (APIs) and advanced materials. This product is essential for research institutions, pharmaceutical manufacturers, and fine chemical companies engaged in the development of neurological and neuromuscular therapeutics, as well as specialty chemical applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of Amifampridine (3,4-DAP phosphate), a medication used to treat Lambert-Eaton myasthenic syndrome (LEMS).
• Neurological Research: Used as a potassium channel blocker in neuroscience research to study synaptic transmission and nerve function.
• Chemical Synthesis: Serves as a versatile precursor for the synthesis of more complex heterocyclic compounds, ligands, and functionalized pyridine derivatives.
• Coordination Chemistry: Acts as a chelating ligand for metal ions in the preparation of catalysts and metal-organic frameworks (MOFs).
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Dye & Pigment Manufacturing: Used in the production of specialized dyes and colorants due to its aromatic amine functionality.

Basic Information

Product Name	3,4-Diaminopyridine
CAS No.	54-96-6
Molecular Formula	C5H7N3
Molecular Weight	109.13 g/mol
Synonyms	3,4-DAP; 3,4-Diaminopyridine; 4-Amino-3-pyridinamine; Pyridine-3,4-diamine; 3,4-Pyridinediamine; Amifampridine Base; 3,4-Diaminopyridine Free Base
EINECS	200-222-5

Quality Control

Our 3,4-Diaminopyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is tested against rigorous in-house specifications, which typically include identification, assay, and impurity profile analysis. Certificates of Analysis (COA) detailing the results of these tests are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.