Description

3,3',5-Triiodothyroacetic Acid is a key iodinated aromatic compound that serves as a critical intermediate and reference standard in pharmaceutical research and development. Its structural similarity to thyroid hormones makes it invaluable for studying metabolic pathways and developing diagnostic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable building blocks for active pharmaceutical ingredient (API) synthesis and biochemical analysis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of thyroid hormone analogs and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in metabolic studies, receptor binding assays, and endocrine system research.
• Diagnostic Agent Development: Serves as a precursor in the development of radioiodinated compounds for diagnostic imaging.
• Fine Chemical Synthesis: Employed in organic synthesis to introduce the triiodophenol moiety into more complex molecular architectures.
• Academic & Industrial R&D: A key material for investigating structure-activity relationships (SAR) in drug discovery programs.

Basic Information

Product Name	3,3',5-Triiodothyroacetic Acid
CAS No.	51-24-1
Molecular Formula	C14H9I3O4
Molecular Weight	621.93 g/mol
Synonyms	Triiodothyroacetic Acid; Tiratricol; TRIAC; 3,3',5-Triiodothyroacetate; 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylacetic Acid; TA3; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine Acetic Acid Derivative; 3,3',5-Triiodo-L-thyronine Acetic Acid
EINECS	200-083-5

Quality Control

Our 3,3',5-Triiodothyroacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.