Description

4,7-Methanoisobenzofuran-1-Ol, 1,3,3A,4,7,7A-Hexahydro-, (1R,3Ar,4S,7R,7As)- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique, rigid molecular framework is valued for constructing complex, three-dimensional architectures with precise stereocontrol. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural complexity can contribute to unique biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands and organocatalysts.
• Fine Chemical & Specialty Material Production: Employed in the manufacture of high-value, performance-oriented chemicals and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and exploring new chemical spaces in discovery research.

Basic Information

Product Name	4,7-Methanoisobenzofuran-1-Ol, 1,3,3A,4,7,7A-Hexahydro-, (1R,3Ar,4S,7R,7As)- (9Ci)
CAS No.	499971-02-7
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1R,3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-4,7-methanoisobenzofuran-1-ol; (1R,3aR,4S,7R,7aS)-Octahydro-4,7-epoxyisobenzofuran-1-ol; 1,3,3a,4,7,7a-Hexahydro-4,7-methanoisobenzofuran-1-ol, (1R,3aR,4S,7R,7aS)-rel-; Bicyclo[2.2.1]hept-5-ene-2-methanol, 1,3,3a,4,7,7a-hexahydro- (stereoisomer); Chiral Hexahydromethanoisobenzofuranol; 499971-02-7; 4,7-Methanoisobenzofuran-1-ol, hexahydro-, (1R,3aR,4S,7R,7aS)-
EINECS	Contact for details

Quality Control

Our production of 4,7-Methanoisobenzofuran-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR, to confirm identity, stereochemical purity, and impurity profile. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.