Description

(11Bs)-N,n-Bis[(R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral organophosphorus compound, specifically a dinaphthodioxaphosphepine derivative. This compound is of significant value as a highly selective ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and advanced chemical synthesis facilities focused on developing novel therapeutic agents and high-value intermediates.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metals (e.g., Rh, Pd, Ir) in enantioselective hydrogenation, C-C bond formation, and other catalytic transformations.
• Pharmaceutical Intermediate Synthesis: A key building block or chiral auxiliary in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring high optical purity.
• Methodology Development: Used in academic and industrial research to develop new catalytic protocols and explore novel reaction pathways in organic chemistry.
• Fine Chemical Production: Enabling the commercial-scale manufacture of enantiomerically enriched flavors, fragrances, and agrochemical intermediates.
• Material Science Research: Potential application in the development of chiral materials, such as liquid crystals or polymers with specific optical properties.

Basic Information

Product Name	(11Bs)-N,n-Bis[(R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No.	497883-22-4
Molecular Formula	C38H32NO2P
Molecular Weight	565.64 g/mol
Synonyms	(11bS)-4-Amino-11b,12b-dihydro-6H,7H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; N,N-Bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (S)-N,N-Bis[(R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; Chiral Dioxaphosphepine Amine Ligand; (R,R)-DACH-Phenyl Dioxaphosphepine Ligand Analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (11Bs)-N,n-Bis[(R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure high chemical and chiral purity, critical for reproducible performance in asymmetric synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and identity are provided with every shipment. We support compliance with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.