Description

Methanone, [4-[(1S)-1-Aminoethyl]Phenyl]Phenyl- CAS NO 482620-71-3 is a chiral aromatic ketone derivative featuring an aminoethyl functional group. This compound serves as a valuable advanced pharmaceutical intermediate (API) and a versatile chiral building block for asymmetric synthesis. It is primarily required by research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or building block for constructing complex molecules with high enantiomeric purity.
• Organic Ligand Synthesis: Used in the preparation of specialized ligands for catalytic systems in chemical manufacturing.
• Research & Development: Critical material for medicinal chemistry programs and process development in academic and industrial labs.
• Fine Chemical Production: Intermediate for manufacturing high-value specialty chemicals, agrochemicals, and performance materials.

Basic Information

Product Name	Methanone, [4-[(1S)-1-Aminoethyl]Phenyl]Phenyl-
CAS No.	482620-71-3
Molecular Formula	C15H15NO
Molecular Weight	225.29 g/mol
Synonyms	(S)-1-[4-(Benzoyl)phenyl]ethylamine; (1S)-1-[4-Benzoylphenyl]ethanamine; (S)-4'-Aminoethylbenzophenone; (S)-1-(4-Benzoylphenyl)ethylamine; Benzophenone, 4'-[(1S)-1-aminoethyl]-; (S)-α-Methyl-4-benzoylbenzylamine
EINECS	Contact for details

Quality Control

Our production of Methanone, [4-[(1S)-1-Aminoethyl]Phenyl]Phenyl- adheres to stringent quality management systems. Each batch is characterized and tested to ensure identity, purity, and chiral integrity, with specifications typically covering assay (HPLC), enantiomeric excess (Chiral HPLC), and related substances. Certificates of Analysis (COA) documenting all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.