Description

2-Fluoro-4-(2-Hydroxy-Ethyl)-Benzoic Acid is a versatile fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a hydroxyethyl group on a fluorinated aromatic ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorine and polar groups into specialty polymers, improving their chemical resistance and surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex fluorinated aromatic compounds via coupling and condensation reactions.
• Chemical Research: Utilized as a standard or reference material in analytical method development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Fluoro-4-(2-Hydroxy-Ethyl)-Benzoic Acid
CAS No.	481075-50-7
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	4-(2-Hydroxyethyl)-2-fluorobenzoic Acid; 2-Fluoro-4-(2-hydroxyethyl)benzoic Acid; Benzoic acid, 2-fluoro-4-(2-hydroxyethyl)-; 2-Fluoro-4-(β-hydroxyethyl)benzoic Acid; 481075-50-7; 4-(2-Hydroxyethyl)-2-fluoro-benzoic Acid; 2-Fluoro-4-(2-Hydroxyethyl)BenzoicAcid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(2-Hydroxy-Ethyl)-Benzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications developed for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.