Description

4-Fluoro-2-Isopropoxyphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, which are prevalent in many drug candidates.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated and alkoxy-substituted phenyl moiety.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides where the specific substitution pattern can influence biological activity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Material Science Research: Incorporated into the synthesis of organic electronic materials, such as those for OLEDs or semiconductors, where fluorine atoms can tune electronic properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	4-Fluoro-2-Isopropoxyphenylboronic Acid
CAS No.	480438-59-3
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(4-Fluoro-2-isopropoxyphenyl)boronic acid; 2-Isopropoxy-4-fluorophenylboronic acid; 4-Fluoro-2-(1-methylethoxy)benzeneboronic acid; 4-Fluoro-2-isopropoxybenzeneboronic acid; Boronic acid, B-[4-fluoro-2-(1-methylethoxy)phenyl]-; 480438-59-3; 4-Fluoro-2-isopropoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.