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3-Fluoro-4-Isopropoxyphenylboronic Acid CAS NO 480438-54-8


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CAS No.:480438-54-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluoro-4-Isopropoxyphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for developing new active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
  • Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
  • Material Science: Serves as a monomer or cross-linker precursor for creating advanced polymers, liquid crystals, and organic electronic materials.
  • Chemical Research: A versatile reagent in academic and industrial laboratories for methodological development in palladium-catalyzed coupling reactions.
  • Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 3-Fluoro-4-Isopropoxyphenylboronic Acid
CAS No. 480438-54-8
Molecular Formula C9H12BFO3
Molecular Weight 197.99 g/mol
Synonyms (3-Fluoro-4-isopropoxyphenyl)boronic acid; 3-Fluoro-4-isopropoxybenzeneboronic acid; 4-Isopropoxy-3-fluorophenylboronic acid; Boronic acid, B-(3-fluoro-4-isopropoxyphenyl)-; 480438-54-8; 3-Fluoro-4-(1-methylethoxy)benzeneboronic acid
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Quality Control

Our 3-Fluoro-4-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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