Description

2-Acetamido-2-Deoxy-D-[2-13C]Glucose is a stable isotope-labeled derivative of N-acetylglucosamine, a fundamental building block in glycobiology. This compound is essential for advanced metabolic and structural studies, providing a non-radioactive, highly sensitive tracer for NMR spectroscopy and mass spectrometry. It is a critical reagent for researchers and manufacturers in pharmaceutical development, biochemical research, and diagnostic assay production, particularly for investigating carbohydrate metabolism, glycosylation pathways, and cell wall biosynthesis.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in NMR and LC-MS studies to elucidate biosynthetic routes and flux analysis of amino sugars and glycoconjugates.
• Glycoprotein & Glycolipid Research: Serves as a labeled precursor for the study of N-linked and O-linked glycosylation processes in therapeutic proteins and cell surface receptors.
• Pharmaceutical Development: Employed in the research and development of glycosidase inhibitors, anti-inflammatory agents, and oncology therapeutics targeting carbohydrate metabolism.
• Diagnostic Reagent Manufacturing: Integrated into the production of high-precision kits for enzymatic assays and clinical diagnostics related to metabolic disorders.
• Biomarker Discovery: Facilitates quantitative proteomics and metabolomics for identifying disease-specific glycosylation patterns.
• Academic & Institutional Research: A key tool in biochemistry, microbiology, and chemical biology labs for fundamental research on chitin, hyaluronic acid, and other glycosaminoglycans.

Basic Information

Product Name	2-Acetamido-2-Deoxy-D-[2-13C]Glucose
CAS No.	478529-39-4
Molecular Formula	C8H1513CNO6
Molecular Weight	222.20 g/mol (for 13C1 isotopologue)
Synonyms	N-Acetyl-D-[2-13C]glucosamine; [2-13C]-N-Acetylglucosamine; 2-Acetamido-2-deoxy-D-glucose-2-13C; GlcNAc-2-13C; NAG-2-13C; 2-(Acetylamino)-2-deoxy-D-[2-13C]glucose; D-[2-13C]GlcNAc
EINECS	Contact for details

Quality Control

Every batch of our 2-Acetamido-2-Deoxy-D-[2-13C]Glucose is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR for isotopic enrichment, HPLC for chemical purity, and specific optical rotation. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic content are provided and traceable to relevant standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Assay (HPLC)	≥ 98.0% (chemical purity)
Specific Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.