Description

Uridine Diphosphate-α-D-[1-13C]Glucose Disodium Salt is a stable isotope-labeled nucleotide sugar essential for tracing and quantifying metabolic flux in glycosylation pathways. This compound is a critical reagent for advanced research in biochemistry and molecular biology, providing a carbon-13 labeled substrate for precise metabolic studies. It is primarily used by researchers and pharmaceutical developers in glycobiology, enzymology, and drug discovery to investigate carbohydrate metabolism and biosynthesis.

Application

• Metabolic Flux Analysis (MFA): As a 13C-labeled tracer for studying glucose utilization and nucleotide sugar metabolism in cell cultures and biological systems.
• Enzyme Kinetics & Mechanism Studies: Substrate for glycosyltransferases (e.g., UGT enzymes) to elucidate reaction mechanisms, kinetics, and inhibition profiles.
• Glycoconjugate Biosynthesis Research: Precursor for the synthesis of labeled glycoproteins, glycolipids, and proteoglycans in vitro.
• Biomarker Discovery & Diagnostic Assay Development: Internal standard for the mass spectrometry (LC-MS/MS, GC-MS) based quantification of UDP-sugars and related metabolites in clinical and biological samples.
• Pharmaceutical R&D: Tool compound for screening and validating novel therapeutics targeting glycosylation pathways in cancer, infectious diseases, and congenital disorders of glycosylation (CDGs).
• Stable Isotope Probing (SIP): Used in microbiological and environmental research to track the activity and pathways of specific microbial communities.

Basic Information

Product Name	Uridine Diphosphate-α-D-[1-13C]Glucose Disodium Salt
CAS No.	478529-38-3
Molecular Formula	C15H22N2Na2O17P2 * (1-13C)
Molecular Weight	Contact for details
Synonyms	UDP-[1-13C]Glucose disodium salt; UDP-α-D-[1-13C]Glucose disodium salt; UDP-Glc-13C1 disodium salt; Uridine 5'-(α-D-[1-13C]glucopyranosyl diphosphate) disodium salt; 1-13C-labeled UDP-glucose; UDP-[1-13C]Glc disodium; Isotope-labeled UDP-glucose; Uridine diphosphoglucose-13C1 disodium salt
EINECS	Contact for details

Quality Control

Every batch of our Uridine Diphosphate-α-D-[1-13C]Glucose Disodium Salt is manufactured and analyzed under strict quality protocols to ensure high chemical purity and isotopic enrichment. Identity, purity, and isotopic composition are verified by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity (e.g., atom % 13C), and impurity profile is provided with each shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Isotopic Enrichment (Atom % 13C)	≥ 99% at the C-1 position
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Functional as substrate for glycosyltransferases

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.