Description

3-o-Methyl-D-[6-13C]Glucose is a stable isotope-labeled analog of glucose, specifically labeled with carbon-13 at the C-6 position and methylated at the 3-O position. This compound is a critical tool for advanced metabolic research, enabling precise tracing of glucose uptake, glycolysis, and related biochemical pathways using techniques like NMR and mass spectrometry. It is essential for researchers and scientists in pharmaceutical development, metabolic disease research, and biochemistry who require high-purity, isotopically labeled tracers for accurate in vitro and in vivo studies.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to quantify intracellular metabolic pathway rates and network regulation.
• Drug Metabolism & Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS for the quantitative analysis of glucose and its metabolites in biological matrices.
• Glycolysis & Pentose Phosphate Pathway Studies: Enables detailed investigation of glucose catabolism and anabolic utilization in cell cultures and model organisms.
• NMR Spectroscopy: Provides a distinct 13C NMR signal for non-invasive, real-time monitoring of metabolic processes.
• Diabetes and Metabolic Disorder Research: Facilitates the study of insulin resistance, glucose transport mechanisms, and cellular energy metabolism.
• Biochemical Assay Development: Employed in the development and validation of high-sensitivity assays for enzyme activity related to glucose metabolism.

Basic Information

Product Name	3-o-Methyl-D-[6-13C]Glucose
CAS No.	478529-34-9
Molecular Formula	C7H1413CO6
Molecular Weight	~209.18 g/mol (for 13C1 isotopologue)
Synonyms	3-O-Methyl-D-glucose-6-13C; D-3-O-Methylglucose-6-13C; 6-13C-3-O-Methyl-D-glucose; 3-Methoxy-D-glucose-6-13C; 3-OMG-6-13C; [6-13C]-3-O-Methyl-D-glucopyranose; Stable Isotope Labeled 3-OMG
EINECS	Contact for details

Quality Control

Every batch of 3-o-Methyl-D-[6-13C]Glucose is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry to confirm structure, isotopic enrichment, and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by atmospheric moisture. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Enrichment (13C)	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.