Description

L-[1-13C]Glucose is a stable isotope-labeled analog of D-glucose, specifically enriched with carbon-13 at the C-1 position. This high-purity biochemical is essential for advanced metabolic research, enabling precise tracing of glucose utilization and carbon flux in biological systems. It is a critical reagent for scientists and manufacturers in pharmaceutical R&D, clinical diagnostics, and metabolic engineering who require uncompromised isotopic purity and chemical stability for accurate in vitro and in vivo studies.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to quantify intracellular metabolic pathway rates in cell cultures, tissues, and whole organisms.
• Pharmaceutical Research: Employed in drug discovery and development to study the effects of new compounds on glucose metabolism and energy homeostasis.
• Clinical Diagnostics & Biomarker Discovery: Serves as a probe in NMR and mass spectrometry-based assays to identify metabolic disorders such as diabetes and cancer.
• Nutritional Science: Utilized to investigate glucose absorption, distribution, and metabolism in nutritional studies.
• Biotechnology & Fermentation: Applied in optimizing microbial and mammalian cell culture processes by tracing carbon sources.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a standard and tracer in 13C-NMR studies for structural and dynamic analysis.

Basic Information

Product Name	L-[1-13C]Glucose
CAS No.	478519-02-7
Molecular Formula	C6H12O6 (with 13C at position 1)
Molecular Weight	181.15 g/mol (approx.)
Synonyms	(1-13C)-L-Glucose; L-Glucose-1-13C; 1-13C-L-Glucose; L-Glucose (1-13C); L-(-)-Glucose-1-13C; Isotopic L-Glucose; [1-13C]-L-Glucose; Stable Isotope Labeled L-Glucose
EINECS	Contact for details

Quality Control

Every batch of L-[1-13C]Glucose is manufactured and analyzed under strict quality management systems to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and LC-MS, to ensure compliance with the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.