Description

2-[2-13C]Acetamido-2-Deoxy-D-Glucose is a stable isotope-labeled analog of N-acetylglucosamine, a fundamental building block in glycobiology and metabolic research. This compound is essential for advanced tracer studies, enabling precise tracking and quantification of metabolic pathways, glycosylation processes, and cell wall biosynthesis. It is a critical reagent for researchers and manufacturers in pharmaceutical development, biochemical research, and diagnostic agent production, where isotopic labeling provides unparalleled analytical accuracy.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study carbohydrate metabolism and glycosylation pathways in cell cultures and model organisms.
• Glycoprotein & Glycolipid Research: Serves as a labeled precursor for investigating the biosynthesis and turnover of complex carbohydrates and glycoconjugates.
• Pharmaceutical R&D: Employed in the development and testing of glycosidase inhibitors, anti-inflammatory agents, and cancer therapeutics that target glycan metabolism.
• Biomarker Discovery & Diagnostics: Utilized in mass spectrometry-based assays for the accurate quantification of glycan biomarkers in biological samples.
• Enzymology Studies: Acts as a substrate for enzymes like hexokinases and glycosyltransferases to elucidate enzyme kinetics and mechanisms.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Provides a sensitive probe for structural and dynamic studies of carbohydrate-containing molecules.

Basic Information

Product Name	2-[2-13C]Acetamido-2-Deoxy-D-Glucose
CAS No.	478518-89-7
Molecular Formula	C8H1513CNO6
Molecular Weight	~222.62 g/mol (for 13C1 isotopologue)
Synonyms	2-Acetamido-2-deoxy-D-[2-13C]glucose; N-Acetyl-D-[2-13C]glucosamine; [2-13C]-GlcNAc; 13C-Labeled N-Acetylglucosamine; 2-(13C)Acetamido-2-deoxy-D-glucose; N-Acetyl-13C-glucosamine; 2-Deoxy-2-[2-13C]acetamido-D-glucose; Labeled GlcNAc
EINECS	Contact for details

Quality Control

Every batch of 2-[2-13C]Acetamido-2-Deoxy-D-Glucose is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Our quality commitment includes NMR and MS verification of isotopic enrichment, rigorous HPLC analysis for chemical purity, and confirmation of optical rotation. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical assay, and identification tests is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Purity (13C)	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.